Heart function in women with preeclampsia after treatment
Not Applicable
Recruiting
- Conditions
- preeclampsiacardiac functionCardiovascular - HypertensionReproductive Health and Childbirth - Fetal medicine and complications of pregnancy
- Registration Number
- ACTRN12612000661875
- Lead Sponsor
- The Royal Women's Hosptial
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Female
- Target Recruitment
- 320
Inclusion Criteria
Women with preeclampsia - non-labouring women, non-smokers, no vasoactive treatments or intravenous fluids adninstered, no previous cardiac disease or uterine abnormality.
Healthy pregnant women - non-labouring women, no significant medical or surgical illness, non smokers, no uterine abnormalities and normally defined placentation. They will not be receiving any vasoactive medication including salbutamol or thyroid replacement hormones.
Exclusion Criteria
labouring women, current administration of vasoactive drugs including salbutamol and thyroxine, pre-existing or gestational diabetes, smoking, and a known uterine abnormality.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method systolic function assessed by transthoracic echocardiography[ at the time of diagnosis of preeclampsia, within 60 minutes of treatment interventions];diastolic function assessed by transthoracic echocardiography[ at the time of diagnosis of preeclampsia, within 60 minutes of treatment interventions]
- Secondary Outcome Measures
Name Time Method cardiac complications - acute pulmonary oedema, arrhythmia, sustained hypertension after treatment, hypotension requiring treatment[ during hospital stay - post birth data obtained from medical record];neurological complications - seizure, blindness, intracerebral haemorrhage or infarction[ during hospital stay - post birth data obtained from medical record];renal complications - renal failure[ during hospital stay - post birth data obtained from medical record];gastrointestinal complications - hepatic rupture, signficantly elevated liver enzymes[ during hospital stay - post birth data obtained from medical record];haematological complications - haemolysis, thrombocytopenia[ during hospital stay - post birth data obtained from medical record];Intensive care admission[ during hospital stay - post birth data obtained from medical record];type of birth[ during hospital stay - post birth data obtained from medical record];Postpartum haemorrhage[ during hospital stay - post birth data obtained from medical record]