Effect of acute exercise on endocannabinoid and mood responses in adults with cancer: A pilot study

Not Applicable

Recruiting

• Conditions: Cancer; Cancer - Any cancer

• Registration Number: ACTRN12623000193673
• Lead Sponsor: Chris O'Brien Lifehouse

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2023-02-23
• Last Update Posted: 21 June 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

Cancer patients: Adults (18 years and older) commenced chemotherapy treatment for a non-haematological cancer with a 2 or 3-weekly protocol; Eastern Cooperative Oncology Group (ECOG) performance status of 0–1, medical approval of the treating oncologist (via email), sufficient English to provide consent and complete study procedures.

Healthy controls: Adults (>18 years); gender-, age- (+/-5 years maximum) and BMI-matched (+/-3.5 kg/m2 maximum) to the recruited cancer patient; no history of systemic cancer treatment; no history of cardiac, metabolic, pulmonary, neurological and/or uncontrolled risk factors; sufficient English to provide consent and complete study procedures.

Exclusion Criteria

•currently using cannabis regularly, for any reason
•any use of cannabis or cannabis products (e.g. CBD oil) within the previous 72 hours
•vigorous exercise or use of complementary therapies such as acupuncture, massage, reflexology, yoga or mindfulness training within 24 hours of the research session
•currently using anti-depressant and/or anxiolytic medication
•continuous use of steroids (i.e. outside of their standard chemotherapy protocol in cancer patients)
•presenting with any absolute or relative contraindication to clinical exercise testing, as defined by the American College of Sports Medicine.

Study & Design

• Study Type: Interventional
• Study Design: Not specified