The Role of TextRAd on Detection of Liver Metastasis in Rectal Cancer
Completed
- Conditions
- Rectal Cancer
- Registration Number
- NCT05398822
- Lead Sponsor
- East Suffolk and North Essex NHS Foundation Trust
- Brief Summary
This is a retrospective analysis of all patients diagnosed with LARC who received NCRT and had MRI scans between 2003-2014 at East Suffolk and North Essex NHS Foundation Trust. Region of interest was drawn around the tumor or its location on T2 MRI images. Six texture parameters were systematically extracted from Textural histograms of post-treatment scans. These parameters were examined to determine their ability to predict local recurrence and distant metastases through Kaplan-Meier survival curves and log-rank tests.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 113
Inclusion Criteria
- All subjects must have MRI post-Chemotherapy treatment to detect the response to Neoadjuvant treatment and compare it to pre-treatment scans to easily determine if there were a posttreatment liver metastasis.
- Locally advanced rectal cancer (LARC) = MRI stage: T3/T4 and/or N1/N0.
Exclusion Criteria
- Distant metastases.
- Synchronous tumour.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Local recurrence of rectal cancer 120 months
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
East Suffolk and North Essex NHS Foundation Trust
🇬🇧Ipswich, United Kingdom