Effects of two types of prebiotics on the intestinal environment and the antibody titers in patients receiving enteral tube feeding: an open-label, randomised controlled trial
Not Applicable
- Conditions
- influenza, diarrhea, constipation
- Registration Number
- JPRN-UMIN000009832
- Lead Sponsor
- Fukushimura Hospital
- Brief Summary
Although there was little difference in the Bifidobacterium count in C group during study period, the Bifidobacterium count in F group increased (about 10-fold). The enhanced HI antibody titers against A/H1N1 and A/H3N2 were maintained in F group for a longer period compared with C group. The seroprotective rates against A/H3N2 in F group at week 6 after influenza vaccination were significantly higher than those in C group.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 23
Inclusion Criteria
Not provided
Exclusion Criteria
1. patients with gastrointestinal disorders such as irritable bowel syndrome and inflammatory bowel disease, or patients with immune diseases, and diabetics 2. other patients judged as inappropriate for the study by the physician in charge
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method antibody titers after influenza vaccination
- Secondary Outcome Measures
Name Time Method microflora and stool form consistency during the study period