Clinical evaluation of yava kshar with gokshuradi kashayam in mutrashmari (Renal calculi)
试验速览
- 阶段
- 2 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- 1) Reduction in the size of calculi
研究概览
简要总结
Mutrashmari is one of the commonest disease of mutravaha Srotas, which is characterised by Pain in nabhi, basti, sevani, mehana, mutradharasangha (obstruction in urine), sarudhiramutrata (Hematuria), mutravikiran (Double stream of urine). Rasatarangini has indicated Yava kshar with Gokshuradi Kashayam as anupara in mutrashmari. This is an open-label, single-arm clinical trial conducted to evaluate the efficacy of Yava Kshara with Gokshuradi Kashaya in the management of Mutrashmari (urinary calculi). Yava Kshara is administered in capsule form at a dose of 1 capsule (500 mg) twice daily, along with 40 ml of Gokshuradi Kashaya as an anupana, taken before meals. The treatment duration is of 3 months, followed by a 1 month of follow-up. A total of 30 patients diagnosed with Mutrashmari is included in the study. The trial is conducted at the Gurukul Campus, Uttarakhand Ayurved University, Haridwar.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Patient having classical signs and symptoms of Mutrashmari will be included.
- •Patients of both sexes and above age of 18 years to 60 years age, irrespective of religion, socioeconomic status, occupation will be taken.
- •Patient having renal calculi with or without mild hydronephrosis will be selected.
- •Radiological evidence of (upto 8 mm) in kidney.
排除标准
- •Complications related to Kidneys/Ureter/Bladder like- Acute Renal Failure, Chronic Renal Failure, Polycystic Kidney diseases, Impaired Renal function.
- •Patients having systemic diseases like RHD, AIDS (Acquired immune deficiency syndrome).
- •Other chronic diseases like TB (Tuberculosis), Hepatitis etc.
- •will be excluded.
- •Pregnant women and lactating mothers will be excluded.
- •Patients having Moderate or severe Hydronephrosis, stag horn calculi will be excluded.
结局指标
主要结局
1) Reduction in the size of calculi
时间窗: 3 months
2) complete expulsion of calculi
时间窗: 3 months
次要结局
- Sign and symptoms of mutrashmari will reduce with treatment(3 months)
研究者
Deeksha Joshi
Gurukul Campus Uttarakhand Ayurved University Haridwar