Prevalence of Coronary Artery Disease in the Siblings of Premature Coronary Heart Disease
- Conditions
- Coronary Heart Disease
- Registration Number
- NCT00918242
- Lead Sponsor
- Yonsei University
- Brief Summary
The aim of this prospective study is to investigate the prevalence of coronary artery disease using computed tomography with family history of premature coronary heart disease
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 87
Inclusion Criteria
- within 1 year
- the siblings of premature coronary heart disease (male<55years old, female<65yeasrs old: Framingham Heart Study) patients admitted relevant hospital
Exclusion Criteria
- Documented coronary heart disease
- experienced adverse events with relevant treatment
- contraindicated with beta-blockers
- Any woman of childbearing potential who is pregnant, seeking to become pregnant or suspects
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method evaluation of prevalence to coronary artery disease using CT within 2 weeks from CT scanning
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms link familial premature CAD to occult coronary artery disease in siblings?
How does CT coronary angiography compare to standard diagnostic methods in detecting CAD in high-risk families?
What biomarkers are associated with increased risk of CAD in siblings of premature CHD patients?
Are there specific adverse events associated with CT screening for CAD in asymptomatic individuals with family history?
What combination approaches or drugs are being explored for CAD prevention in high-risk populations with genetic predisposition?
Trial Locations
- Locations (1)
Yonsei University Severance Hospital
🇰🇷Seoul, Korea, Republic of