Effect of Inspiratory Muscle Training on Posture in Chronic Obstructive Pulmonary Disease Patients

Not Applicable

• Conditions: Chronic Obstructive Pulmonary Disease
• Interventions: Other: Pulmonary rehabilitation

• Registration Number: NCT04117399
• Lead Sponsor: Faculty of Medicine, Sousse

Brief Summary

Chronic obstructive pulmonary disease (COPD) is a respiratory disease that results in progressive airflow limitation and respiratory distress. Physiopathological features of COPD suggest that people who suffer from this disease have many risk factors for falls that have been identified in older individuals. Risk of falls is multi-factorial and impaired balance has been shown to contribute.

The investigators aimed to demonstrate that, IMT performed during a PRP may improve Postural control in COPD patients.

Detailed Description

Chronic obstructive pulmonary disease COPD is a preventable and treatable disease. According to the WHO, COPD would be the third leading cause of death by 2030. This disease is characterized by airflow limitation that is not fully reversible. The airflow limitation is usually progressive and associated with an abnormal inflammatory response of the lung to noxious particles or gases. However, emerging data showed that COPD patients demonstrate important deficits in balance and control which associated to a high risk of fall.

Individuals with COPD, especially those with inspiratory muscle weakness, increased their reliance on ankle muscle proprioceptive signals and decreased their reliance on back muscle proprioceptive signals during balance control, resulting in a decreased postural stability compared to healthy controls. These proprioceptive changes may be due to an impaired postural contribution of the inspiratory muscles to trunk stability.

Inspiratory muscle training (IMT) has been shown to be an effective modality for COPD patients for improving the maximal inspiratory muscle strength, the dyspnea and health-related quality of life. However, the effect of inspiratory muscle training on postural control is not studying. The purpose of this study is to evaluate the effect of the inspiratory muscles training on posture in COPD patients.

Study Timeline

• Study Start: 2019-02-01
• Study First Submitted: 2019-09-28
• Status Verified: 2019-10
• Study First Submitted QC: 2019-10-03
• Last Update Submitted: 2019-10-03
• Study First Posted: 2019-10-07
• Last Update Posted: 2019-10-07
• Primary Completion: 2019-11-15
• Study Completion: 2019-11-15

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: Male
• Target Recruitment: 34

Inclusion Criteria

• Were COPD diagnosed by pulmonary function testing
• Clinically stable
• Abscence of other obstructive diseases
• Signed written consert

Exclusion Criteria

• Were previous pneumonectomy or lobectomy in the past 6 months
• Spontaneous risk of pneumothorax or rib fracture
• Incapacity to follow a standard rehabilitation programme (locomotor deficits, acute cardiac failure and acute exacerbation of COPD at the beginning of the programme)
• Lower limb injury
• Neurological injury or disease
• The absence of written informed consent

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
IMT group	Pulmonary rehabilitation	Inspiratory muscle training + aerobic exercice
Control group	Pulmonary rehabilitation	aerobic exercice

Primary Outcome Measures

Name	Time	Method
Balance outcomes	Basline, After 2 months	Balance were measured by stabilometry to evaluate postural control in COPD patients. Two principals variabels were evaluated: the center of pressure in the mediolateral direction (CoP ML) ; the center of presure in anteroposterior direction (CoP AP).

Trial Locations

Locations (1)

Bilel TOUNSI; 🇹🇳 Sousse, Tunisia