Genetic Registry for Rheumatoid Arthritis
- Conditions
- Rheumatoid Arthritis
- Registration Number
- NCT00069472
- Lead Sponsor
- Northwell Health
- Brief Summary
Many genes are thought to contribute to rheumatoid arthritis (RA). This study will attempt to identify genes that may contribute to RA.
- Detailed Description
The identification of genes for complex disorders such as RA requires large numbers of genetically informative families. This study enrolls people diagnosed with with RA and their families.
This study will enroll 1000 RA patients and their parents. Participants with RA will be evaluated at his or her doctor's office or other location convenient for the participant. Participants will have a brief phone interview with a study coordinator and a blood sample will be obtained. Disease evaluation will be done at one visit and will include confirmation of diagnosis, a 28 joint count, joint alignment and mobility score (JAMS) and administration of a health assessment questionnaire.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 1062
- Adult onset RA
- Diagnosis of RA made between 18 and 60 years old
- Both parents alive and willing to participate
- Parents may have diagnosis of RA (affected) or be unaffected
- Inflammatory bowel disease
- Lupus
- Psoriatic arthritis
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Genetic Association with risk for rheumatoid arthritis 10 years The project aims to identify risk alleles for rheumatoid arthritis using association methods in trio families, combined with data from singleton cases and multiplex families
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Feinstein Institute for Medical Research
🇺🇸Manhasset, New York, United States