Comparison of topical and oral treatments of melasma
Phase 3
- Conditions
- Melasma.Chloasma
- Registration Number
- IRCT201411033566N7
- Lead Sponsor
- Vice chancellor for research, Tabriz University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 90
Inclusion Criteria
Inclusion criterion:patients with facial melasma; patients between 20 and 70 years old. Exclusion criteria: pregnancy; underlying skin diseases; thyroid disease; history of drug allergy; previous use of contraceptives or phenytoin; patients with uncontrolled hypertension; patients with skin infections such as Impetigo; a history of coagulation or thrombosis; skin peeling treatments to treat existing disease; persons aged less than 20 years and more than 70 years old.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The extent of facial skin involvement in percentage. Timepoint: At the first visit and then monthly up to 3 months. Method of measurement: Usin MASI scoring system.;Degree of melasma darkness compairing to normal skin. Timepoint: At the first visit and then monthly up to 3 months. Method of measurement: Usin MASI scoring system.;Homogeneity of the melasma hyperpigmentation. Timepoint: At the first visit and then monthly up to 3 months. Method of measurement: Usin MASI scoring system.
- Secondary Outcome Measures
Name Time Method