Use of Platelet Rich Plasma (PRP) for Improving Thin Endometrium

Not Applicable

Completed

• Conditions: Poor Endometrium
• Interventions: Other: Treatment of Thin Endometrium

• Registration Number: NCT03166345
• Lead Sponsor: Ibn Sina Hospital

Brief Summary

Platelets rich plasma is simple source of growth factors and cytokines that can regulate endometrial growth for subgroup of thin endometrium women. It is an autologous source of this enhancing factors; therefore, there os no risk of using it within the same participant.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2017-05-18
• Study First Submitted QC: 2017-05-22
• Study First Posted: 2017-05-25
• Study Start: 2017-08-15
• Primary Completion: 2018-03-30
• Study Completion: 2018-04-01
• Status Verified: 2018-07
• Last Update Submitted: 2018-07-11
• Last Update Posted: 2018-07-12

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 150

Inclusion Criteria

• women with thin endometrium

Exclusion Criteria

• serum positive hepatitis B and C women

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
PRP injection into Uterine Cavity	Treatment of Thin Endometrium	PRP injection into Uterine Cavity For Treatment of Thin Endometrium
CSF (colony stimulating factor)	Treatment of Thin Endometrium	CSF for Treatment of Thin Endometrium

Primary Outcome Measures

Name	Time	Method
Mean Diameter of endometrial thickness	2 days	How the endometrium would respond after 2 days of PRP

Secondary Outcome Measures

Name	Time	Method
Clinical pregnancy rate	4 weeks or beyond after embryo Transfer	Registered fetal heartbeat 4 weeks or beyond after embryo transfer.

Trial Locations

Locations (2)

IbnSina IVF Center, IbnSina Hospital; 🇪🇬 Sohag, Egypt

Gannah IVF unit, Gannah Hospital; 🇪🇬 Giza, Egypt