The ROX index in the Emergency Department – predicting NIV failure: a prospective observational study
- Conditions
- Emergency medicine - ResuscitationShortness of breathRespiratory - Other respiratory disorders / diseases
- Registration Number
- ACTRN12620000431921
- Lead Sponsor
- iverpool Hospital Emergency Department
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 200
This pragmatic study will include all patients aged 18 or over who are commenced on NIV for breathlessness in the ED, as judged by the treating clinician, regardless of predicted underlying pathology. Breathlessness will be defined by the treating clinician, who will routinely use subjective markers of a patient’s work of breathing as part of clinical assessment, combined with objective data on gas exchange
Prior advanced care directive specifying ’not for intubation’
Comorbidities & disease severity where clinician/family provide limitations of care (i.e. not for intubation or ICU)
NIV utilised as a pre-oxygenation strategy with intention to intubate
Patients electively intubated for diagnostic or therapeutic procedures, such as fibreoptic bronchoscopy and surgery
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method ROX index value as assessed by comparison to data from routinely collected observations and other patient variable data.[12 hours ];The utility of the ROX index to predict NIV failure, defined as progression to intubation. Intubation rates will be determined by reviewing hospital records. [12 hours ]
- Secondary Outcome Measures
Name Time Method ROX index data linked to underlying clinical diagnosis as assessed by the final diagnosis on hospital record upon patient discharge. We hope to use the data collected to sub-categories ROX indices for specific pathologies. This will be the same prospectively collected data as already collected. [12 hours ]