Use of Ketamine in Severe Pain Syndromes

Completed

• Conditions: Pain, Intractable; Pain Syndrome; Pain Measurement; Pain, Chronic

• Registration Number: NCT06537375
• Lead Sponsor: Erasme University Hospital

Brief Summary

Ketamine has been shown to have a certain efficiency in chronic pain syndromes. However, it is still not clearly known what is its efficiency and how ketamine is used in real world patients. In this retrospective study, all patients treated with ketamine for chronic pain in our hospital will be reviewed. Patients demographics, pain syndromes as well as outcome criteria will be collected to describe the use of ketamine in pain syndromes.

Detailed Description

The American Society of Regional Anesthesia and Pain Medicine, together with the American Academy of Pain and the American Society of Anesthesiologists published a consensus guideline in 2018 on the use of ketamine in chronic pain. A review of medical charts of all patients who received ketamine for chronic pain between january 2010 and june 2024 will be done. Demographic data, detailed pain scores, as well as description of the type of pain will be collected. Ketamine usage will be recorded for the dosage, as well as duration of the treatment. Outcome will be measured by before/after pain scores for neuropathic pain, as well as on a visual analog scale. A more global score (good-medium-no effect) will also be collected to get the patient's impression on their treatment. Concomitant pain medication will be collected.

Study Timeline

• Status Verified: 2024-08
• Study Start: 2024-08-01
• Study First Submitted: 2024-08-01
• Study First Submitted QC: 2024-08-01
• Study First Posted: 2024-08-05
• Primary Completion: 2025-02-20
• Study Completion: 2025-02-20
• Last Update Submitted: 2025-02-24
• Last Update Posted: 2025-02-25

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 89

Inclusion Criteria

• All patients who received ketamine as treatment for a pain syndrome during january 2010 until june 2024 at Erasme University Hospital

Exclusion Criteria

• Age < 18 years
• Patients who expressed their opposition to the use of their medical data
• incomplete medical chart

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
VAS	6 month	Visual analog scale of the pain intensity
Patient satisfaction	6 month	A scale (good-medium-no effect) of the efficacity of ketamine on their pain syndrome
DN4	6 month	Neuropathic pain scale 4

Secondary Outcome Measures

Name	Time	Method
Concomitant pain medications	6 month	Number of concomitant pain medications used by the patient

Trial Locations

Locations (1)

Hôpital Universitaire de Bruxelles - Hôpital erasme; 🇧🇪 Brussels, Belgium