Prophylactic Antibiotic Use in Hernioplasty
Phase 3
Completed
- Conditions
- Inguinal Hernia
- Registration Number
- NCT00636831
- Lead Sponsor
- Nihon University
- Brief Summary
The purpose of this study is to determine whether prophylactic antibiotic use in inguinal hernioplasty are effective in prevention of infectious complication.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 400
Inclusion Criteria
- Primary inguinal hernia
- Elective surgery
- Must be older than 20 years of age
- Must not have any serious complication
Exclusion Criteria
- Incarceration
- Recurrence
- Drug allergy
- Diabetes mellitus
- Malignant diseases
- Serious heart diseases
- Psychological diseases
- Pregnancy
- Have been medicated with corticosteroids
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Primary Outcome Measures
Name Time Method infectious complication two year
- Secondary Outcome Measures
Name Time Method Recurrence of inguinal hernia two year
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What are the molecular mechanisms by which prophylactic antibiotics prevent surgical site infections in inguinal hernioplasty?
How does the efficacy of prophylactic antibiotic use in NCT00636831 compare to standard-of-care protocols for hernia surgery?
Are there specific biomarkers that identify patients at high risk of postoperative infection following inguinal hernioplasty?
What are the potential adverse events associated with long-term prophylactic antibiotic use in hernia repair and their management?
What combination therapies or alternative prophylactic agents have been studied for preventing infections in inguinal hernioplasty?
Trial Locations
- Locations (1)
Nihon University School of Medicine, Department of Surgery
🇯🇵Tokyo, Japan
Nihon University School of Medicine, Department of Surgery🇯🇵Tokyo, Japan