The role of the use of steroids intravenously, intratympanically or in combination in the treatment of idiopathic sudden sensorineural hearing loss.

Completed

• Conditions: Idiopathic sudden sensorineural hearing loss; Ear - Deafness

• Registration Number: ACTRN12613001032741
• Lead Sponsor: Medical School of Aristotle University of Thessaloniki

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2013-09-17
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 75

Inclusion Criteria

Idiopathic sudden sensorineural hearing loss

Exclusion Criteria

1) Patients that seeked medical assistance after more than 14 days from the initiation of symptoms.
2) Patients with bilateral sudden sensorineural hearing loss.
3) Patients that have already received treatment for this reason.
4) Patients with known causes of sudden sensorineural hearing loss such as Meniere disease, autoimmune disease, syphilis, trauma, ototoxic agents.
5) MRI of brain and cerebellopontine angle indicative of acoustic neuroma or other retrocochlear lesion (eg demyelinating disease) that can cause sudden sensorineural hearing loss.
6) Pregnancy or breast feeding.
7) Patients younger than 18 years old.
8) History of psychic disorders.
9) History of glaucoma.
10) Active inflammation of the affected ear.
11) Tympanic membrane perforation at the side of the disease.
12) Diabetes mellitus (glucose level higher than 180 mg/ml at baseline)
13) Hypertension (systolic blood pressure higher than 180 mmHg or diastolic blood pressure higher than 110 mmHg at the baseline).
14) Contraindications for the use of steroids (peptic ulcer, osteoporosis, immune suppression).

Study & Design

• Study Type: Interventional
• Study Design: Not specified