The Neural Correlates of Mood and Cognitive Bias in a Population at Risk for Depression: Maternal Cognitive and Emotional Functioning
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 240
- 试验地点
- 2
- 主要终点
- Onset of depression
研究概览
简要总结
The purpose of this study is to investigate risk factors associated with depression and how such factors might be transmitted cross-generationally. The investigators are conducting an integrative assessment of emotion regulation and stress reactivity in a group of mothers with and without a history of depression and their daughters.
详细描述
The purpose of this study is to investigate risk factors associated with depression and how such factors might be transmitted cross-generationally. We are conducting an integrative assessment of emotion regulation and stress reactivity in a group of mothers with and without a history of depression and their daughters. We use a range of methodologies to evaluate these processes, including self-report measures, information-processing performance, HPA-axis functioning and reactivity, and neural responses to emotional stimuli following exposure to stressful experiences.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 9 Years 至 15 Years（Child）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Eligible mothers must read and speak English fluently and have a child between the ages of 9 and 15 years old.
- •Mothers must either have no history of psychopathology or have a history of depression during their child's lifetime.
排除标准
- •Eligible mothers cannot:
- •currently be in treatment for drug or alcohol abuse
- •have significant symptomatology related to psychopathology outside of depression
- •have a medical history of neurological injury or impairment.
- •Mothers who meet the requirements for inclusion in the control group must not have a history of any Axis I disorder.
结局指标
主要结局
Onset of depression
时间窗: 18 months
participants are interviewed in an 18-month follow-up session
次要结局
未报告次要终点