Effect of Cold Air Cooling on the Incidence of Post Inflammatory Hyperpigmentation Following Laser Treatment
Not Applicable
Completed
- Conditions
- NevusHyperpigmentation
- Interventions
- Device: Cold air cooling
- Registration Number
- NCT00287001
- Lead Sponsor
- Mahidol University
- Brief Summary
- To investigate the benefit of epidermal cooling on the incidence of post inflammatory hyperpigmentation after laser irradiation
- Detailed Description
* 70% incidence of post inflammatory hyperpigmentation has been reported following a Q-switched nd:YAG laser treatment of acquired bilateral nevus of Ota-like macules.
* We assumed that epidermal cooling may minimize the non-specific injury to the epidermis caused during laser irradiation, leading to the decreased incidence of post inflammatory hyperpigmentation.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
- Subjects with acquired bilateral nevus of Ota-like macules.
- At least 18 years old
- No previous treatment on the condition for a minimum period of 1 month.
Exclusion Criteria
- Subjects diagnosed of scleroderma, connective tissue disorders, hematologic disorders, hepatitis, infection, or uncontrolled DM
- History of keloid and/or hypertrophic scar.
- Currently on anti-coagulant
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description 1 Cold air cooling 1= cool air cooling
- Primary Outcome Measures
Name Time Method Incidence of post inflammatory hyperpigmentation 2 weeks
- Secondary Outcome Measures
Name Time Method Side effects of cold air cooling and clearing rate of pigmented lesion 12 weeks
Trial Locations
- Locations (1)
Department of Dermatology, Siriraj Hospital, Mahidol University
🇹ðŸ‡Bangkok, Thailand