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Clinical Trials/CTRI/2025/03/081561
CTRI/2025/03/081561Not yet recruitingPhase 3

A randomised controlled trial comparinganaesthetic efficacy of 0.5 percentage Bupivacaine and0.5 percentage Levobupivacaine in supra-clavicularbrachial plexus block with peripheral nervestimulator in upper limb surgeries.

Manisha1 site in 1 country60 target enrollmentStarted: December 3, 2025Last updated:
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Trial Snapshot

Phase
Phase 3
Status
Not yet recruiting
Sponsor
Enrollment
60
Locations
1
Primary Endpoint
1. Onset and duration of Sensory block
Study OverviewStudy DesignEligibility CriteriaOutcomesInvestigatorsSitesRecords & IdentifiersSimilar Trials

Study Overview

Brief Summary

This study has been planned with an aim to compare the effectiveness of bupivacaine and levobupivacaine in supraclavicular brachial plexus block and to compare onset and duration of sensory ,motor blockade,duration of analgesia and hemodynamic parameters among patients undergoing upper limb surgeries.

Study Design

Study Type
Interventional
Allocation
Computer generated randomization
Masking
Participant, Investigator and Outcome Assessor Blinded

Eligibility Criteria

Ages
18.00 Year(s) to 60.00 Year(s) (—)
Sex
All

Inclusion Criteria

  • •Patients of either sex, aged 18–60 years, belonging to American Society of Anesthesiologists(ASA) physical status class I and II willing to participate in the study.

Exclusion Criteria

  • •Who refuses to give consent.
  • •With severe cardiac, renal, endocrine, pulmonary disease.
  • •Who are allergic to study drugs.
  • •Who is having a local site infection.
  • •With hemi-diaphragmatic paralysis on opposite side of surgery
  • •With any psychological disorder who would interfere with assessment of pain.
  • •With a history of brachial plexus injury.
  • •With bilateral upper limb surgery and fracture.

Outcomes

Primary Outcomes

1. Onset and duration of Sensory block

Time Frame: Onset of sensory and motor blockade will be monitored every two minutes for the first 20 | minutes and then every five minutes till 30 minutes.

2. Onset and duration of motor block

Time Frame: Onset of sensory and motor blockade will be monitored every two minutes for the first 20 | minutes and then every five minutes till 30 minutes.

Secondary Outcomes

  • 1. Hemodynamic parameters including HR, SBP, DBP(2. Complications include hypotension, bradycardia, pneumothorax,nausea, vomiting and)

Investigators

Sponsor
Manisha
Sponsor Class
Other [self]

Study Sites (1)

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