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临床试验/NCT03662243
NCT03662243已完成不适用

Treatment for Reading and Writing Deficits Following Acquired Brain Injury

Quality Living, Inc.1 个研究点 分布在 1 个国家目标入组 2 人开始时间: 2018年8月30日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
2
试验地点
1
主要终点
Change in score on Word Attack subtest of the Woodcock-Johnson III Test of Achievement.

研究概览

简要总结

Many people with acquired brain injuries have deficits in reading decoding, reading comprehension, and written expression. Alexia is a phenomenon in which a person who previously could read has trouble doing so after having sustained a brain injury; likewise, agraphia is an acquired writing problem affecting one or more aspects of written communication. Alexia and agraphia sometimes co-occur with one another and/or with other language challenges, but they can also occur as isolated phenomena. Methods to treat alexia and agraphia often focus on single intervention techniques that address aspects of reading or writing in isolation-such as matching written and spoken letters or letter sounds, performing choral reading, tracing letters, etc. Existing research suggests that the effectiveness of these techniques is limited. However, when used in combination, such techniques may promote improved reading and written communication skills. As such, the purpose of this research is to determine the extent to which a multicomponent intervention program improves the reading and writing capabilities of people with acquired alexia and/or agraphia.

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Prospective

入排标准

年龄范围
14 Years 至 70 Years(Child, Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Survivor of acquired brain injury
  • Exhibits alexia and/or agraphia
  • Past or current client of Quality Living, Inc., Omaha, Nebraska
  • Fluent speaker of English

排除标准

  • Vision impairment prohibiting reading of 24-point text
  • Auditory comprehension problems precluding understanding of consent/assent information

结局指标

主要结局

Change in score on Word Attack subtest of the Woodcock-Johnson III Test of Achievement.

时间窗: Change from baseline at 8 weeks

Subtest raw sores range from 0 to 32,with higher scores indicating better performance.

Change in score on Word Reading subtest of the Wide Range Achievement Test 4.

时间窗: Change from baseline at 8 weeks

Subtest raw scores range from 0 to 70, with higher scores indicating better performance.

Change in score on Spelling subtest of the Wide Range Achievement Test 4.

时间窗: Change from baseline at 8 weeks

Subtest raw scores range from 0 to 57, with higher scores indicating better performance.

Change in score on Test of Silent Reading Speed and Efficiency.

时间窗: Change from baseline at 8 weeks

Raw scores range from 0 to 70, with higher scores indicating better performance.

Change in score on Passage Comprehension subtest of the Woodcock-Johnson III Test of Achievement.

时间窗: Change from baseline at 8 weeks

Subtest raw scores range from 0 to 47, with higher scores indicating better performance.

次要结局

  • Decoding errors during oral reading of passages(As the first of five tasks of each session for 8 weeks (each session is 1 hour).)
  • Oral spelling of words(As the second of five tasks of each session for 8 weeks (each session is 1 hour).)
  • Sight word decoding accuracy(One time per week for 8 weeks)
  • Oral reading rate of passages(As the first of five tasks of each session for 8 weeks (each session is 1 hour).)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Karen Hux

Director of Research

Quality Living, Inc.

研究点 (1)

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