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Clinical Trials/NCT03662243
NCT03662243
Completed
N/A

Treatment for Reading and Writing Deficits Following Acquired Brain Injury

Quality Living, Inc.1 site in 1 country2 target enrollmentAugust 30, 2018

Overview

Phase
N/A
Intervention
Not specified
Conditions
Acquired Brain Injury
Sponsor
Quality Living, Inc.
Enrollment
2
Locations
1
Primary Endpoint
Change in score on Word Attack subtest of the Woodcock-Johnson III Test of Achievement.
Status
Completed
Last Updated
5 years ago

Overview

Brief Summary

Many people with acquired brain injuries have deficits in reading decoding, reading comprehension, and written expression. Alexia is a phenomenon in which a person who previously could read has trouble doing so after having sustained a brain injury; likewise, agraphia is an acquired writing problem affecting one or more aspects of written communication. Alexia and agraphia sometimes co-occur with one another and/or with other language challenges, but they can also occur as isolated phenomena. Methods to treat alexia and agraphia often focus on single intervention techniques that address aspects of reading or writing in isolation-such as matching written and spoken letters or letter sounds, performing choral reading, tracing letters, etc. Existing research suggests that the effectiveness of these techniques is limited. However, when used in combination, such techniques may promote improved reading and written communication skills. As such, the purpose of this research is to determine the extent to which a multicomponent intervention program improves the reading and writing capabilities of people with acquired alexia and/or agraphia.

Registry
clinicaltrials.gov
Start Date
August 30, 2018
End Date
September 15, 2020
Last Updated
5 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Karen Hux

Director of Research

Quality Living, Inc.

Eligibility Criteria

Inclusion Criteria

  • Survivor of acquired brain injury
  • Exhibits alexia and/or agraphia
  • Past or current client of Quality Living, Inc., Omaha, Nebraska
  • Fluent speaker of English

Exclusion Criteria

  • Vision impairment prohibiting reading of 24-point text
  • Auditory comprehension problems precluding understanding of consent/assent information

Outcomes

Primary Outcomes

Change in score on Word Attack subtest of the Woodcock-Johnson III Test of Achievement.

Time Frame: Change from baseline at 8 weeks

Subtest raw sores range from 0 to 32,with higher scores indicating better performance.

Change in score on Word Reading subtest of the Wide Range Achievement Test 4.

Time Frame: Change from baseline at 8 weeks

Subtest raw scores range from 0 to 70, with higher scores indicating better performance.

Change in score on Spelling subtest of the Wide Range Achievement Test 4.

Time Frame: Change from baseline at 8 weeks

Subtest raw scores range from 0 to 57, with higher scores indicating better performance.

Change in score on Test of Silent Reading Speed and Efficiency.

Time Frame: Change from baseline at 8 weeks

Raw scores range from 0 to 70, with higher scores indicating better performance.

Change in score on Passage Comprehension subtest of the Woodcock-Johnson III Test of Achievement.

Time Frame: Change from baseline at 8 weeks

Subtest raw scores range from 0 to 47, with higher scores indicating better performance.

Secondary Outcomes

  • Decoding errors during oral reading of passages(As the first of five tasks of each session for 8 weeks (each session is 1 hour).)
  • Oral spelling of words(As the second of five tasks of each session for 8 weeks (each session is 1 hour).)
  • Sight word decoding accuracy(One time per week for 8 weeks)
  • Oral reading rate of passages(As the first of five tasks of each session for 8 weeks (each session is 1 hour).)

Study Sites (1)

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