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Clinical Trials/NCT00064805
NCT00064805
Completed
Not Applicable

Cognitively-based Treatments of Acquired Dyslexias

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)1 site in 1 country58 target enrollmentAugust 2002

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Dyslexia, Acquired
Sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Enrollment
58
Locations
1
Primary Endpoint
Improved accuracy and/or speed of reading individual words aloud.
Status
Completed
Last Updated
11 years ago

Overview

Brief Summary

Adults who sustain brain damage due to stroke, head injury, or traumatic surgery may develop difficulty reading. This study examines the effectiveness of behavior-based programs to improve reading ability in these individuals.

Detailed Description

Acquired disorders of reading (acquired dyslexia) are common in patients with aphasia subsequent to left hemisphere stroke. Even when language functions recover sufficiently to enable the patient to return to work, continuing dyslexia often interferes significantly with job performance. This study will evaluate cognitive therapies for the treatment of acquired dyslexia. Each therapy is based upon a cognitive neuropsychological model of reading; the therapies target specific types of reading deficit and stem from the question of re-learning versus re-organization of function. The therapies focus on dyslexic disorders stemming from the following underlying deficits: 1) impaired access to the orthographic word form from the visual modality (pure alexia); 2) impaired orthographic/phonologic connections (phonologic/deep dyslexia); and 3) decreased ability to hold phonologic codes in memory (phonologic text alexia). Participants in this study will undergo a comprehensive and detailed battery of reading and reading-related tests to determine the underlying impairment causing the reading deficit. Based upon the results of these tests, the patient's dyslexic disorder will be characterized and, if appropriate, the patient will be assigned to one of the treatment programs devised specifically for that type of deficit. Treatment programs are evaluated for efficacy by comparing the accuracy and speed of reading pre- and post-treatment.

Registry
clinicaltrials.gov
Start Date
August 2002
End Date
July 2007
Last Updated
11 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Eligibility Criteria

Inclusion Criteria

  • Not provided

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

Improved accuracy and/or speed of reading individual words aloud.

Secondary Outcomes

  • Improved accuracy and/or speed of reading text aloud.

Study Sites (1)

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