PITUItary Carcinomas or Aggressive Tumors REgistry: Monocentric Study Form a Cohort of Patient Operated on for Pituitary Tumors in University Hospital of Lyon (France)
试验速览
- 阶段
- 不适用
- 入组人数
- 1,300
- 试验地点
- 1
- 主要终点
- Progression free survival after pituitary surgery according to the clinicopathological classification (HYPOPRONOS)
研究概览
简要总结
The purpose of this study is to observe predictors of pituitary tumor recurrence and markers of persistent disease activity through computerized collection of comprehensive demographic, therapeutic, pathologic and outcome information on patients harboring pituitary mass lesions of all types.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients with confirmed pituitary disease
排除标准
- •patients who do not have confirmed pituitary disease
结局指标
主要结局
Progression free survival after pituitary surgery according to the clinicopathological classification (HYPOPRONOS)
时间窗: up to 10 years (postoperatively)
Clinical, biochemical et imaging evaluation of a cohort of patient operated in the referral center for pituitary tumor. Identification of recurrence or progression an analysis of the clinicopathological classification. Evaluation of the different therapeutic strategies (med, surgery, chemotherapies, radiation therapy) to prevent recurrence or tumor progression.
次要结局
- Correlation between percentage of SSTR expression of the pituitary tumor and somatostatine analogs efficacy.(2007-2020)
- Correlation between percentage of MGMT expression of the pituitary tumor and tumor response to temozolomide.(2007-2020)