Single-injection Adductor Canal Block for Total Knee Arthroplasty Under Spinal Anesthesia

Not Applicable

Completed

• Conditions: Total Knee Arthroplasty
• Interventions: Procedure: control group; Procedure: adductor canal block

• Registration Number: NCT04400708
• Lead Sponsor: Seoul National University Hospital

Brief Summary

This study evaluates the effect of the single-injection adductor canal block in patients receiving total knee arthroplasty under spinal anesthesia.

Detailed Description

This study aims to evaluate the effect of the single-injection adductor canal block in patients receiving total knee arthroplasty under spinal anesthesia. The effect of the single-injection adductor canal and continuous adductor canal block in patients receiving total knee arthroplasty under general anesthesia has been well established. However, due to the residual effect of spinal anesthesia, the effect of the single-injection adductor canal block needs to be determined. The investigators hypothesize that the single-injection adductor canal block will decrease the total sum of 2h, 6h, 12h, and 24h pain score.

Study Timeline

• Study First Submitted: 2020-05-19
• Study First Submitted QC: 2020-05-21
• Study First Posted: 2020-05-22
• Study Start: 2020-05-28
• Primary Completion: 2021-06-22
• Study Completion: 2021-06-29
• Status Verified: 2023-11
• Last Update Submitted: 2023-11-21
• Last Update Posted: 2023-11-24

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

• adult patients receiving total-knee arthroplasty under spinal anesthesia
• ASA class 1-3

Exclusion Criteria

• infection at the needle injection site
• hard for pain evaluation
• CRPS patient with lower extremity symptom
• chronic opioid user
• those with side effect to local anesthetics
• those getting revision total-knee arthroplasty or with the previous operation at the same knee area
• those getting the surgery under general anesthesia due to the failed spinal anesthesia

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
control group	control group	normal saline injection
test group	adductor canal block	0.5% ropivacaine injection

Primary Outcome Measures

Name	Time	Method
the sum of pain score	2 hours, 6 hours, 12 hours, and 24 hours after intervention	VAS pain score (0 to 10) is measured using numeric pain rating scale at 2 hours, 6 hours, 12 hours, and 24 hours 0: no pain, 10: worst pain

Secondary Outcome Measures

Name	Time	Method
Postoperative opioid consumption	2 hours, 6 hours, 12 hours, and 24 hours intervention	amount of postoperative opioid consumption based on oral morphine equivalent daily dose
Postoperative nausea and vomiting	2 hours, 6 hours, 12 hours, and 24 hours after intervention	degree of postoperative nausea and vomiting (0 to 3) 0: no nausea, no vomiting, 1: nausea present, but no vomiting, 2: nausea present, vomiting once, 3: vomiting repeatedly within 30 minutes.

Trial Locations

Locations (1)

Seoul National University Hospital; 🇰🇷 Seoul, Korea, Republic of