Effects of cytokine for antidepressant treatment in Cancer Patients with depression

Chonnam National University Hospital0 个研究点目标入组 60 人开始时间: 待定最近更新: 2019年3月11日

适应症

试验速览

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•1)Pregnancy or breastfeeding
•2)Severe physical illnesses threatening life within 1 month
•3)History of neuropsychiatric illnesses such as dementia, Parkinson's disease, alcoholism, and other substance dependence, mental retardation, leraning disorder
•4)history of headtrauma, stroke
•5)history of brain tumor, both primary or metastatic
•6)atrial fibrillation, myocardial infarction within 1 month
•7)Persistent clinically significant laboratory abnormalities
•:patient with high bleeding tendency like low platelet(<130 x 103/mm2)
•8)terminal cancer patient with life expectancy within 6 month
•9)other psychiatric disorder on DSM-IV Axis I
•10) history of delirium within 1 month
•11)history of unknown or uncontrolled seizure attack at least one, well documented epilepsy
•12)unknown cause of neutropenia
•13) bilirubin, SGPT, SGOT,ALP level above 3 times more than normal upper limit
•14) serum creatine>1.4mg/dl
•15)history of severe allergic or multiple drug adverse reaction
•16)participation in other clinical reserach and then take other prescripted medication
•17)depressive episode with psychotic features
•18) high risk of suicide
•19)previous bipolar disorder, family history of schizophrenia

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