Head Elevation in Prone Position
Phase 2
Completed
- Conditions
- Gas ExchangeLung Mechanics
- Interventions
- Procedure: Prone position with head elevation
- Registration Number
- NCT00753129
- Lead Sponsor
- Medical University of Vienna
- Brief Summary
Semi-recumbent position leads to improvement of gas exchange and lung mechanics in patients suffering from ALI or ARDS. Prone positioning leads to similar effects. To date, no data on the combination of these two positioning measures exist. The investigators hypothesize that head elevation in prone position leads to improvement in gas exchange and lung mechanics.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
- Mechanically ventilated
- ALI or ARDS
- No contraindications for prone position
Exclusion Criteria
- Patient < 18 or > 89 years old
- Pregnancy
- Elevated intracranial pressure
- PaO2/FiO2 - ratio < 60
- ECMO
- Open abdomen
- Instable spine
- Malignant arrhythmias
- Severe hemodynamic instability
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Arm && Interventions
Group Intervention Description 1 Prone position with head elevation Start with turning to prone position without head elevation, after 2 hours 30° head elevation, after 2 hours back to PP without head elevation. 2 Prone position with head elevation Start with turning to prone position with 30° head elevation, after 2 hours PP without head elevation, after 2 hours back to 0° PP.
- Primary Outcome Measures
Name Time Method PaO2/FiO2 ratio Study period (5 hours on 2 consecutive days)
- Secondary Outcome Measures
Name Time Method PaCO2, Compliance (Chest wall, lung, respiratory system) Study period (5 hours on 2 consecutive days)
Trial Locations
- Locations (1)
Dept. of Internal Medicine I, Intensive Care Unit, Medical University of Vienna
🇦🇹Vienna, Austria