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Analysis of lung ventilation during prone positioning of patients with Acute Respiratory Distress Syndrome (ARDS) using Electrical Impedance Tomography (EIT)

Recruiting
Conditions
J80
Adult respiratory distress syndrome
Registration Number
DRKS00009555
Lead Sponsor
Medizinische Fakultät der Universität Leipzig
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
30
Inclusion Criteria

1. Decision of the treating physicians to use prone positioning and electrical impedance tomography to detect lung ventilation
2. Prone positioning of the Patient according to our hospital's standard operating procedure
3. Diagnosis of ARDS according to the Berlin Definition (PaO2/FiO2 Ratio below 300mmHg, see ARDS Definition Task Force, JAMA 2012)

Exclusion Criteria

Patients, where electrical impedance tomography is not used

Study & Design

Study Type
observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Detection of a shift in lung ventilation towards dorsal parts of the lung during prone positioning using electric impedance tomography
Secondary Outcome Measures
NameTimeMethod
1. Detection of recruitment of poorly aerated lung regions by prone positioning<br>2. Detection of an increment in the amount of aerated lung volume by prone positioning<br>3. Proof of a correlation between quantitative computer tomography parameters (distribution of atelectasis, lung weight) and improvement of gas exchange due to prone positioning<br>4. Proof of a minor degree of skin irritations by prone positioning and electrical impedance tomography measurements<br>5. Comparison of electrical impedance tomography and PV-Loop (LIP) for determination of the best PEEP
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