The Presence of Microbes in the Sperm and Their Impact on Sperm Capacitation and IVF Treatment
试验速览
- 阶段
- 不适用
- 入组人数
- 200
- 主要终点
- The percent of successful IFV treatments
研究概览
简要总结
Study Goals:
- Finding the prevalence of bacteria of the sperm in an innovative and more accurate methode
- Understanding the effect of microbes on the process of capacitation
- The impact of microbes in the sperm on IVF success rate
- Finding the incidence of vaginal bacteria and their relationship to bacteria of the sperm
- The impact of vaginal flora on IVF success rate
详细描述
Prospective non interventional study in the Department of Life Sciences, Bar-Ilan University and IVF Unit at Meir Hospital.
The control group consisting of 50 semen samples from men with no sperm problems and 50 vaginal samples from their partners.
The study group consisting of 50 semen samples from men with male fertility problems and 50 vaginal samples from their partners.
The semen taken from the remains after fertilization of the IVF laboratory. (Liquid otherwise routinely thrown).
Vaginal samples taken from women undergoing IVF treatment under anesthesia after informed consent.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Male and female undergoing fertility treatments
排除标准
- •Male and female not undergoing fertility treatments
结局指标
主要结局
The percent of successful IFV treatments
时间窗: 24 months
Using 16-S Ribosomal RNA analysis to quantify and compare (type and percentages) of bacterial components in sperm samples from fertile and infertile men and their impact on IVF treatments success rate
次要结局
未报告次要终点