Effect of adapted computerized cognitive training on executive functions and anxiety symptoms, compared to a standard intervention in patients with mild neurocognitive disorder at a mental health institution in Manizales: a randomized clinical experimental study

niversidad de Manizales0 sites100 target enrollmentSeptember 6, 2024

Overview

No summary available.

Registry

who.int

Start Date

September 6, 2024

End Date

March 30, 2025

Last Updated

last year

Study Type

Interventional

Sex

All

Sponsor

niversidad de Manizales

•1\. Diagnosis of MCI according to Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM\-5\) criteria, with symptom onset within the last 2 years and diagnosed by the neuropsychology department at least 6 months prior to inclusion
•2\. Score on the Montreal Cognitive Assessment (MOCA) between \=15\.1 and \=20\.5
•3\. Preservation of complex instrumental activities of daily living with the possibility of using compensatory strategies according to a score of 8 on the Lawton and Brody scale
•4\. Preservation of basic activities of daily living with a Barthel Index score between 91 and 100, indicating mild dependence or complete independence, sufficient for participation in the study
•5\. A minimum of 5 years of formal education
•6\. Mild anxiety symptoms according to the Beck Anxiety Inventory (BAI) score, between 8 and 15
•7\. Impairment in executive functions according to scores obtained in the study tests (Card Sorting from the BANFE\-2: Standardized score \=7, Alphabetical Ordering from the BANFE\-2 (trial 2 and 3\): Standardized score \=7, Digit Retention from the WAIS\-IV: Scaled scores \=7, Arithmetic from the WAIS\-IV: Scaled scores \=7, Corsi Blocks: Scaled score \=7, Stroop Test Form A and B from the BANFE\-2: Standardized score \=7, Working Memory Index from the WAIS\-IV: Scores \=85\)
•8\. Sufficient visual and/or auditory acuity to perform neuropsychological tests

•1\. Associated neurological disorders
•2\. Scores on the Yesavage Geriatric Depression Scale (GDS\-15\) that do not indicate moderate to severe depressive symptoms (scores \<6\)
•3\. Psychiatric comorbidity other than anxiety symptoms
•4\. History of addiction within the last 10 years
•5\. Receiving cognitive training during the last 6 months prior to starting participation in the study
•6\. Hospitalization in an Intermediate Care or Intensive Care Unit within the last year