跳至主要内容
临床试验/CTRI/2023/05/052557
CTRI/2023/05/052557尚未招募不适用

Comparative evaluation of socket preservation in anterior teeth using Allograft Vs Probiotic and collagen membrane -A Cone Beam Computed Tomography Analysis

Panineeya Institute of dental sciences1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2023年5月20日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
30
试验地点
1
主要终点
the healing of extracted socket will be evaluated

研究概览

简要总结

SOCKET PRESERVATION: Socket preservation or alveolar ridge preservation is a procedure to reduce bone loss after tooth extraction After tooth extraction, the jaw bone has a natural tendency to become narrow, and lose its original shape because the bone quickly resorbs, resulting in 30–60% loss in bone volume in the first six months. Bone loss, can compromise the ability to replace the tooth or its aesthetic and functional ability.

Demineralized freeze-dried bone allograft (DFDBA) Is a graft composed of demineralized bone matrix It is effective in the reconstruction of bone defects and has also demonstrated osteo inductive properties. When implanted in bone that is already well-vascularized, it has the ability to stimulate cell attachment, cell migration, and osteogenesis. It causes new bone formation to take place during healing and is a commonly used material for bone enhancement and bone development processes.

Probiotics are used to help in the recolonization of beneficial bacteria as well as to modulate the immune response. They have been stated to help in wound healing also. They are available in the form of gels, lozenges, tablets and chewing gum.

研究设计

研究类型
Interventional
分配方式
Not Applicable
盲法
Participant and Outcome Assessor Blinded

入排标准

年龄范围
25.00 Year(s) 至 50.00 Year(s)(—)
性别
All

入选标准

  • Extraction of Maxillary or mandibular non restorable single rooted teeth.
  • Presence of teeth adjacent to extracted socket.

排除标准

  • Participants who are smokers Pregnant and lactating woman.
  • Patients having motor difficulties that impede or hamper hygiene Immunocompromised individuals and patients with metabolic bone diseases or who have undergone radiotherapy in the last five years.

结局指标

主要结局

the healing of extracted socket will be evaluated

时间窗: baseline,one week

次要结局

  • Which monotherapy will be more effective allograft or probiotic in the healing of extracted socket Will combination therapy allograft plus probioticbe more benificial in the healing of extracted socket

研究者

发起方
Panineeya Institute of dental sciences
申办方类型
Research institution and hospital

研究点 (1)

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