nderstanding the influence of pain and spinal cord stimulation on evoked potentials and EEG
Completed
- Conditions
- chronic neuropathic painchronic pain as a result from injury to the nervous system10041543
- Registration Number
- NL-OMON37470
- Lead Sponsor
- Medisch Spectrum Twente
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patients: patients who participated in a trial for a new form of stimulation (burst stimulation) and in whom EP and EEG measurements are performed during the case they still had classing (tonic) stimulation and during the case they had two week burst stimulation.
Controls: aged matched volunteers
Exclusion Criteria
Patients: hospitalisation or other form of serious decline of general health
Controls: Chronic pain, former brain surgery, diagnosed neurological disease
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The amplitudes of the reconstructed signal of the primary somatosensory cortex<br /><br>(S1) evoked by stimulation of Aβ-fibers and Aδ-fibers and pain scores,<br /><br>determined by a visual analog score (VAS). These amplitudes and pain scores<br /><br>will be compared in the tonic SCS, burst SCS, SCS off and controls. </p><br>
- Secondary Outcome Measures
Name Time Method <p>Secondairy study parameters are the activity of other brain areas after Aβ<br /><br>and Aδ stimulation. In the rest EEG this activity is measured as power per<br /><br>frequency band. Other study parameters are the presence of allodynia,<br /><br>experience of paresthesias, pain scores per body part and quality of the pain<br /><br>(sharp, burning, etc.) </p><br>