nderstanding the influence of pain and spinal cord stimulation on evoked potentials and EEG.
- Conditions
- Chronic neuropathic pain - Chronische neuropatische pijnSpinal cord stimulation - Ruggermerg stimulatieEEG Evoked potentials (EP)
- Registration Number
- NL-OMON20960
- Lead Sponsor
- Prof. M.J.A.M van Putten MD PhDClinical Neurophysiologist Medisch Spectrum Twentet.: 053 487 2810e-mail: m.vanputten@mst.nl
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 60
Inclusion Criteria
A patient group and a control group will be included.
Exclusion Criteria
Patients:
Hospitalisation or other form of serious decline of general health.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The amplitudes of the reconstructed signal of the primary somatosensory cortex (S1) evoked by stimulation of Aβ-fibers and Aδ-fibers and pain scores, determined by a visual analog score (VAS). These amplitudes and pain scores will be compared in the tonic SCS, burst SCS, SCS off and controls.
- Secondary Outcome Measures
Name Time Method Secondairy study parameters are the activity of other brain areas after Aβ and Aδ stimulation. In the rest EEG this activity is measured as power per frequency band. Other study parameters are the presence of allodynia, experience of paresthesias, pain scores per body part and quality of the pain (sharp, burning, etc.)