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Effect of Oral L-carnitine Supplement on Lipid Profile, Anemia, and Quality of Life of Patients

Phase 2
Completed
Conditions
Complication of Hemodialysis
Interventions
Drug: placebo
Registration Number
NCT01278693
Lead Sponsor
Isfahan University of Medical Sciences
Brief Summary

The purpose of this study is to determine Effect of oral L-carnitine supplement on lipid profile, anemia, and quality of life.

Detailed Description

In patients under maintenance hemodialysis several factors reduce the body stored carnitine which in turn affected dyslipidemia, anemia, and general health in these patients. The investigators evaluated the effect of oral L-carnitine supplementation on lipid profiles, anemia, and quality of life in hemodialysis patients.

Recruitment & Eligibility

Status
COMPLETED
Sex
Female
Target Recruitment
54
Inclusion Criteria

being in the age range of 18-75 having the history of at least 12 weeks of hemodialysis and at least three times a week and each session almost for four hours having serum triglyceride or total cholesterol concentration >200 mg/dl or serum HDL concentration >40 mg/dl in the beginning of the study.

Exclusion Criteria

taking carnitine supplement or the drug that interact with carnation lowering the seizure threshold in the last month being affected by liver function abnormalities, hypothyroidism, chronic infectious diseases (such as hepatitis), inflammatory diseases, CNS mass having the history of seizure.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
placeboplaceboit is as like as L-carnitine in shape
L-carnitineL-carnitineit is kind of supplement
Primary Outcome Measures
NameTimeMethod
lipid profileat sixteen weeks after admission
Secondary Outcome Measures
NameTimeMethod
anemiaat sixteen weeks after admission
quality of lifeat sixteen weeks after admission

Trial Locations

Locations (1)

Noor university hospital

🇮🇷

Isfahan, Iran, Islamic Republic of

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