Comparison of different doses of bupivacaine in labor spinal analgesia
Phase 2
- Conditions
- labor analgesia.Complication of anaesthesia during labour and delivery, unspecified
- Registration Number
- IRCT201701168768N5
- Lead Sponsor
- Vice chancellor for Research and Technology, Hamadan University Of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 40
Inclusion Criteria
ASA 1 primigravid singletone parturients with gestational age (36-40 wk) in active phase of labor (cervix dilation 4-6 cm)
Exclusion criteria: Use of analgesic or opioids in recent 12 hours; chronic hypertension; preeclampsia; gestational diabetes; allergy to drugs; cardiovascular disease; coagulopathy
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Onset of analgesia. Timepoint: every 5 minutes after spinal injection. Method of measurement: Time from spinal injection until the relief of labor pain in the first 15 min such that the subject did not request rescue medication.(pain VAS<4).;Duration of analgesia. Timepoint: every 15 minutes after spinal injection. Method of measurement: Time from spinal injection until the end of spinal analgesia.(minute).
- Secondary Outcome Measures
Name Time Method Pruritus. Timepoint: every 15 minutes after spinal injection until the end of spinal analgesia. Method of measurement: VAS for pruritus (0-10).;Nausea and vomiting. Timepoint: every 15 minutes after spinal injection until the end of spinal analgesia. Method of measurement: yes/no question from patient.;Motor bockade. Timepoint: every 15 minutes after spinal injection. Method of measurement: Bromage Scale (1=no motor block--ability to raise extended leg against gravity; 2 = inability to raise extended leg, able to bend knee; 3 = inability to bend knee, able to flex ankle; and 4 = complete motor block) were assessed at the 3 levels.;Neonatal Apgar score. Timepoint: 1 and 5 minutes after birth. Method of measurement: Apgar scale.;Sensory level to cold and pinprick. Timepoint: 15 minutes after spinal injection. Method of measurement: question from patient in response to cold and pinprick (dermatomal level).