Multimodal Postoperative Analgesia Following OSA Surgery

Not Applicable

• Conditions: Obstructive Sleep Apnea

• Registration Number: NCT04483427
• Lead Sponsor: Bahaa Mohammed Refaie

Brief Summary

Assessment of the clinical efficacy and adverse effects of multimodal analgesic regimen consisting of nalbuphine combined with ketorolac using IV continuous infusion silicon device (Accufuser) for postoperative analgesia following multilevel OSA surgeries

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2020-07-16
• Study First Submitted QC: 2020-07-20
• Study First Posted: 2020-07-23
• Study Start: 2020-09-20
• Status Verified: 2021-09
• Last Update Submitted: 2021-09-26
• Last Update Posted: 2021-09-28
• Primary Completion: 2022-07
• Study Completion: 2022-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• physical status of American Society of Anesthesiologists (ASA) II
• age between 30 - 50 years
• OSA patients diagnosed by polysomnography and stop-bang questionnaire
• enrolled for multilevel OSA surgery

Exclusion Criteria

• history of allergy to the study drugs
• history of hepatic, cardiopulmonary or renal disease
• history of any chronic pain on medication
• history of substance abuse
• psychiatric disorder
• lack of patient cooperation.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
Postoperative pain	Assessment will be carried out 48 hours postoperatively	Visual analog pain score

Secondary Outcome Measures

Name	Time	Method
incidence of adverse effects	48 hours postoperatively	hypoxia, nausea, vomiting, itching
Sedation level	48 hours postoperatively	Ramsey Sedation Ramsey Sedation Scale

Trial Locations

Locations (1)

Sohag faculty of medicine; 🇪🇬 Sohag, Egypt