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The Effects of Gonadotropin Replacement Therapy in Patients With Hypogonadism

Completed
Conditions
Idiopathic Hypogonadotropic Hypogonadism
Interventions
Registration Number
NCT02042638
Lead Sponsor
Gulhane School of Medicine
Brief Summary

Effects of hCG replacement therapy on metabolic syndrome parameters in hypogonadotrophic hypogonadism.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
Male
Target Recruitment
16
Inclusion Criteria

Serum testosterone concentration < 300ng/dL Absence of a pituitary or hypothalamic mass lesions, Presence of gonadotropin response to GnRH, -

Exclusion Criteria

Previous androgen treatment, diabetes mellitus, arterial hypertension other hormone deficiencies

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
16 treatment naive Hypogonadotropic hypogonadism patientsPregnyl (hCG) ampule 1500 IU/three times a weekTreatment naive 16 patients with idiopathic hypogonadotrophic hypogonadism
16 treatment naive Hypogonadotropic hypogonadism patientshCG 1500 IU three times a weekTreatment naive 16 patients with idiopathic hypogonadotrophic hypogonadism
Primary Outcome Measures
NameTimeMethod
HDL after hCG treatment2011-2013

2011-2013

total cholesterole levels after hCG treatment2011-2013
LDL levels after hCG treatment2011-2013
Secondary Outcome Measures
NameTimeMethod
Body fat ratio after hCG treatment2011-2013
hsCRP levels after hCG treatment2011-2013

Trial Locations

Locations (1)

Gulhane School of Medicine Dep. of Endocrinology and Metabolism

🇹🇷

Ankara, Turkey

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