Discontinuation of antidementia medication in extremely severe dementia patients: a 12-week randomized multicenter trial
Not Applicable
Recruiting
- Conditions
- Diseases of the nervous system
- Registration Number
- KCT0000874
- Lead Sponsor
- Bobath Memorial Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 120
Inclusion Criteria
1. Patients fulfilling DSM-IV criteria for dementia
2. Patients fulfilling NINCDS-ADRDA possible or probable AD (Alzheimer’s disease)
3. aged between 65 to 100 years old
4. caregiver who can give full information about patient should exist
5. same antidementia and antipsychotic medications at least 2 months before study enrollment
6. patients who can visit hospital at every follow up
7. K-MMSE =5 and FAST score 6a or less
Exclusion Criteria
1. severe uncontrolled medical condition
2. other degenerative brain diesase or psychiatric disease which can cause dementia
3. 2 or more antidementia medication(excluding brain pill).
4. patients or caregivers do not accept the study
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method BPMSE score;CGI-C score
- Secondary Outcome Measures
Name Time Method ESDQ score;NPI score;CMAI score;CDR score;CDR-SOB score;FAST score;ADCS-ADL-severe score;K-MMSE score;B-ADL score;HIS (Hachinski ischemic scale) score;study-related medical complication ;study-related mortality