A Comparison between three different doses of clonidine for decreasing stress response to endotracheal intubation during surgery
Phase 1
- Conditions
- Health Condition 1: 4- Measurement and Monitoring
- Registration Number
- CTRI/2023/08/056600
- Lead Sponsor
- Department of Anaesthesia, ABVIMS and Dr.RML Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.American Society Of Anaesthesiology (ASA) 1 and 2.Elective surgical Procedures
3.Either Sex
4.Consenting Adults Of age 18 to 55 Years
Exclusion Criteria
1.Known sensitivity to any study drug
2.Pregnant females
3.Pateint with chronic hypertension and diabetes mellitus
4. Patient with history of cardiac and respirtaory disease
5.Patient with anticipated difficult airway
6.Patient with impaired kidney and liver function
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Hemodynamic Response to Endotracheal Intubation (Heart rate, SBP & DBP, MAP)Timepoint: Hemodynamic Response to Endotracheal Intubation (Heart rate, SBP & DBP, MAP) after 1 and 3 and 5 minute of endotracheal intubation
- Secondary Outcome Measures
Name Time Method Biochemical markers of stress response (Serum Cortisol & Blood glucose levels)Timepoint: 5 minutes following Laryngoscopy & Endotracheal intubation