To see the safety and effect of drug clonidine in low dose on Blood Pressure & Heart Rate in patients undergoing Laproscopic Cholecystectomy
Not Applicable
- Conditions
- Health Condition 1: null- patients of cholelithasis who will undergo laproscopic cholecystectomy
- Registration Number
- CTRI/2012/05/002641
- Lead Sponsor
- Subharti Medical College Meerut
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 120
Inclusion Criteria
ASA grade 1 and 2 undergoing laproscopic cholecystectomy
Exclusion Criteria
Morbid obese
hypertension
Renal,Caddiac, cerebrovascular, Hepatic diseases and endocrine dysfunction
Alcohol/ Drug abuse
Patients taking antidepressatns/ antihypertensives/ antiepileptic drugs
Pregnancy
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method to find the efficacy of different low doses intravenous clonidine on hemodynamic stability during intubation,pneumoperitoneum and extubationTimepoint: Preoperatively ,after study drug ,1 min after induction,1 min & 5 min after intubation,before pneumoperitoneum ,at 5,10,20,30,40min after pneumoperitonium ,just after extubation ,post operatively at 15 and 30 minutes
- Secondary Outcome Measures
Name Time Method 1).To study the efficacy of low dose clonidine on anesthesia requirement and recovery profile <br/ ><br>2). To compare the efficacy of different doses of clonidine on hemodynamic stability, anesthesia requirement and recovery profileTimepoint: 1)time to extubation <br/ ><br>2)recovery time- time to response to verbal commands(spontaneous eye opening)and orintation time( to recollect name, date of birth and location)