Treatment of hyperpigmented spots on human ski
- Conditions
- Volar forearms with solar Lentigines, but otherwise healthy skinSkin and Connective Tissue Diseases
- Registration Number
- ISRCTN19231900
- Lead Sponsor
- Beiersdorf AG
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 20
1. Females/ males between 50 and 70 years of age in generally good health
2. Solar Lentigines on the arms but otherwise healthy, undamaged skin in the test sites
3. Fitzpatrick skin phototype I, II, III or IV
4. Ability to understand the study concept (intellectual capacity and language skills) and to comply with the test schedule and study rules
5. Participant is willing and able to give written informed consent
1. Active, acute skin ailments in the test sites, for example atopic Dermatitis or eczema
2. Changes to the skin which conflict with study goals
3. Systemic or topical medication which counteract study objectives
4. Medications, taken either orally or applied topically within the last 4 weeks, which impair immune reactions, for example cytostatic agents and cortisone
5. Severe general illness, either currently or within the last 12 months, for example malignant tumor, severe diabetes, severe cardiovascular disease (e.g. cerebral apoplexy, myocardial infarction, bypass or decompensated high blood pressure)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Skin colour contrast of lentigines to surrounding skin is measured using a spectrophotometer at baseline, 4,8, and 12 weeks.
- Secondary Outcome Measures
Name Time Method 1. The size and colour of the lentiginous spots is measured using photographs at baseline, 4, 8, and 12 weeks<br>2. The forearm skin is measured using visual inspections at baseline, 4, 8, 12 weeks for signs of irritation