The Effects of Maintenance a Remifentanil Infusion on the Hemodynamic Variables and Recovery Quality
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 42
- 试验地点
- 1
- 主要终点
- Smooth cLMA Removal Condition (Score 1)
研究概览
简要总结
The effect of maintenance remifentanil infusion with target controlled infusion during laryngeal mask airway removal on hemodynamic parameters and emergence quality is going to be investigated.
详细描述
In all patients (control group and remifentanil group induction of anesthesia will be achieved with desflurane and remifentanil.Anesthesia will be maintained with remifentanil (1-4 ng/mL) by TCI target controlled infusion, and desflurane . Throughout the surgery hemodynamic parameters are going to be recorded. As soon as the surgery has been finished, in control group remifentanil infusion and desflurane inhalation is going to be stopped.In remifentanil group,desflurane inhalation is going to be stopped and remifentanil infusion will be maintained until the removal of LMA. During the emergence period the time of eye opening, hemodynamic parameters and emergence quality (score 1-2)are going to be recorded.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •ASA I-II status
- •aged 18-60 years old
- •presenting for ureterorenoscopy
排除标准
- •history of hypertension
- •asthma and chronic obstructive lung disease
- •recent respiratory tract infections
研究组 & 干预措施
ultiva,remifentanil,opioid,analgesic
Remifentanil:1.5ng/ml remifentanil infusion maintained at the end of the surgery
干预措施: remifentanil (Drug)
结局指标
主要结局
Smooth cLMA Removal Condition (Score 1)
时间窗: At the end of the surgery
cLMA removal was accepted as successful (score 1) if none of the complications coughing, teeth clenching, gross purposeful movements, breath holding, laryngospasm, and desatura- tion to SpO2\\90% was observed. If any of these compli- cations was observed it was regarded as unsuccessful (score 2)
次要结局
未报告次要终点
研究者
derya özkan
MD consultant
Diskapi Teaching and Research Hospital