Quality of life in patients with postsurgical hypoparathyroidism
Recruiting
- Conditions
- Parathyroid disease
- Registration Number
- NL-OMON28953
- Lead Sponsor
- Erasmus Medical Centre
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 225
Inclusion Criteria
In order to be eligible to participate in this study, a subject must meet all of the following criteria:
-Patients who are aged 18 years or older at the time of inclusion
-Patients who gave informed consent
-Both cases and controls underwent (completion) thyroidectomy
-Cases have persisting hypoparathyroidism according to the previously mentioned definition and controls do not
Exclusion Criteria
A potential subject who meets any of the following criteria will be excluded from participation in this study:
-Patients who are not able to provide written informed consent
-No adequate understanding of the Dutch language
-Parathyroid disease or parathyroid surgery
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The primary objective of this study are:<br>- To assess the physical quality of life in patients with hypoparathyroidism as measured by the SF-36 questionnaire. <br>- To determine the Thyroid-Related quality of life in patients with hypoparathyrodism <br>- To determine the cognitive and functional outcomes in patients with hypoparathyrodism<br>- To determine the burden of disease in patients with hypoparathyroidism
- Secondary Outcome Measures
Name Time Method The secondary objective of this study is to the determine the burden of disease in patients with hypoparathyroidism, attributed to hypoparathyroidism and hypoparathyroidism treatment by measuring medication use, the absence of work/return to work, extra hospital visits, comorbidities, hypoparathyroidism related laboratory parameters.