Evaluation of PET Scan Timing Relative to AV-45 Injection Time
- Conditions
- Alzheimer's Disease
- Registration Number
- NCT01565356
- Lead Sponsor
- Avid Radiopharmaceuticals
- Brief Summary
This study will re-read 10-minute positron emission tomography (PET) scans acquired in previous clinical studies of AV-45 at 30 and 50 minutes after injection and compare the results.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 41
Not provided
Not provided
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Primary Outcome Measures
Name Time Method Percent Agreement of Interpretation Between 30-40 and 50-60 Min Reads - Qualitative Evaluation Scans acquired 30-40 min and 50-60 min after injection Three independent readers blinded to subject identification, subject diagnosis, subject demographics and PET scan time points post-injection read each scan and reported as amyloid positive or amyloid negative. Results show the percentage of agreement between the majority read of 30-40 min scan and the majority read of the 50-60 min scan.
- Secondary Outcome Measures
Name Time Method Agreement of Interpretation Between 30-40 and 50-60 Min Reads - Semi-quantitative Evaluation Scans acquired 30-40 min and 50-60 min post-injection Three independent readers blinded to subject identification, subject diagnosis, subject demographics and PET scan time points post-injection read each scan and reported the results using a 5-point scale (0=no amyloid; 4=high levels of amyloid deposition). Results are reported as a weighted kappa statistic.