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Assess the Effect of Daily Purgation therapy with small doses of medicine alongwith External panchakarma therapy in Diabetic peripheral neuropathy disease

Phase 3
Completed
Conditions
Health Condition 1: - Health Condition 2: - Health Condition 3: G64- Other disorders of peripheral nervous systemHealth Condition 4: G63- Polyneuropathy in diseases classified elsewhere
Registration Number
CTRI/2022/03/041400
Lead Sponsor
Institute of Teaching and Research in Ayurveda
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
20
Inclusion Criteria

1)Known case of type2 diabetes mellitus.

2)Presence of any classical symptoms-

Burning sensation

Pain

Numbness

Tingling sensation

Insensitivity to hot or cold in feet.

3)Patients of both genders.

Exclusion Criteria

1)Patients having any other associated clinical complication like

cancer

T.B

Local skin infection

wound

Diabetic foot

2)Type1 diabetes.

3)Age below 30 years and age above 75years.

4)Pregnant and Lactating women.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
1)Observing signs and symptoms of Patients in Diabetic peripheral neuropathy- Tingling sensation,Numbness,Burning sensation,Prickling sensation through symptoms grading score. <br/ ><br>2)Modified toronto clinical neuropathy score(mTCNs) <br/ ><br>3)Vibration and Thermal threshold test by Neuropathy analyser machine Biothesiometer. <br/ ><br>4)Monofilament test <br/ ><br>5)Laboratory invetigation- <br/ ><br>FBS,PP2BS <br/ ><br>LIPID PROFILE <br/ ><br>URINE INV. <br/ ><br>Haematological <br/ ><br>Vitamin B12(before treatment ) <br/ ><br>Timepoint: Before starting of Treatment and after 15 days of completion of treatment
Secondary Outcome Measures
NameTimeMethod
1)Changes in signs and symptoms of Diabetic peripheral neuropathy <br/ ><br>2)changes in Modified toronto clinical neuropathy score <br/ ><br>3)changes in Biothesiometer reading <br/ ><br>4)changes in monofilament test <br/ ><br>5)changes in FBS and PP2BS <br/ ><br>Timepoint: Patients will be assessed before treatment and after 15days completion of treatment
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