Evaluation of State and Shade of White Spot Lesions After Using Different Remineralizing Agents (An in Vivo Study)

Not Applicable

Completed

• Conditions: White Spot Lesion
• Interventions: Other: Biomimetic remineralizing agent; Other: Resin Modified Glass Ionomer Varnish

• Registration Number: NCT04671134
• Lead Sponsor: Al-Azhar University

Brief Summary

The aim of the study is to evaluate the effect of Biomimetic remineralizing agent and resin modified glass ionomer varnish on color shade and state of white spot lesions immediately, after 3 months, and after 6 months. (An in vivo study).

Detailed Description

Not available

Study Timeline

• Study Start: 2017-06-01
• Primary Completion: 2018-12-01
• Study Completion: 2019-06-01
• Status Verified: 2020-12
• Study First Submitted: 2020-12-08
• Study First Submitted QC: 2020-12-11
• Last Update Submitted: 2020-12-11
• Study First Posted: 2020-12-17
• Last Update Posted: 2020-12-17

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

1. Patients included in this clinical trial were less than 30 years old.
2. Patients with good general health.
3. Patients who will agree to the consent and will commit to follow-up period.
4. Fully erupted anterior teeth with no cavitated lesions.

Exclusion Criteria

1. Patients with any systemic disease that may affect normal healing.
2. Patient with bad oral hygiene.
3. Tetracycline or florosis staining.
4. Patients who could/would not participate in all times of follow-up.
5. Untreated periodontal disease was not allowed.
6. Active caries or defective Restorations in 6 anterior teeth.
7. Bleaching history
8. Patients participating in more than 1 dental study.
9. Patient received fluoride varnish before.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Resin modified glass ionomer varnish	Biomimetic remineralizing agent	-
Biomimetic remineralizing agent	Resin Modified Glass Ionomer Varnish	-
Resin modified glass ionomer varnish	Resin Modified Glass Ionomer Varnish	-
Biomimetic remineralizing agent	Biomimetic remineralizing agent	-

Primary Outcome Measures

Name	Time	Method
state of lesions	6 months.	Digital scores

Secondary Outcome Measures

Name	Time	Method
shade of lesions	6 months	Digital scores

Trial Locations

Locations (1)

Al-Azhar University; 🇪🇬 Cairo, Egypt