A randomised placebo controlled crossover trial to evaluate the effects of different doses of taurocholic acid in a suppository on gastrointestinal hormone secretion and appetite in healthy humans.

Phase 1

Completed

• Conditions: Type 2 diabetes mellitus; Obesity; Metabolic and Endocrine - Diabetes; Diet and Nutrition - Obesity

• Registration Number: ACTRN12610000520033
• Lead Sponsor: Royal Adelaide Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2010-06-23
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: Male
• Target Recruitment: 12

Inclusion Criteria

Haemoglobin > 135 g/

Exclusion Criteria

Medications affecting gut function
Alcohol intake >20g daily or cigarette smoking
Significant gastrointestinal disease or surgery
Impaired liver or renal function
Blood donation within 3 months

Study & Design

• Study Type: Interventional
• Study Design: Not specified