Observational Study on Cerebro- and Cardio-vascular Complication in Predialysis, Hemodialysis, and Peritoneal Dialysis Patients with Chronic Kidney Disease
Not Applicable
Recruiting
- Conditions
- Chronic kidney disease
- Registration Number
- JPRN-UMIN000001589
- Lead Sponsor
- Department of Integrated Therapy for Chronic Kidney Disease, Graduate School of Medical Sciences, Kyushu University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 300
Inclusion Criteria
Not provided
Exclusion Criteria
1. Pregnant women, or women who have a possibility of pregnancy 2. Patients using acidic dialysate 3. Patients who have previously received another dialysis therapy for over 3 months 4. Patients who have previously undergone renal transplantation
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. Alteration of brain volume in MRI 2. Alteration of calcification score in coronary CT
- Secondary Outcome Measures
Name Time Method 1. Incidence rate of overt cerebro- and cardio-vascular complications 2. Intima-media thickness of common carotid artery 3. Cardiac function examined by echocardiography and cine-MRI 4. Pulse wave velocity examined by MRI 5. Augmentation Index (AI) 6. Bone mineral density examined by dual-energy X-ray absorptiometry 7. Residual renal function 8. Higher brain function quantified using Japan Stroke Scale Higher Cortical Function (JSS-H) 9. Quality of life quantified using the Kidney Disease Quality of Life Short Form (KDQOL-SF)