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The effect of submucosal injection of platelet rich plasma and perforations in alveolar bone for reducing the time required for correction of cramped lower jaw front teeth using fixed orthodontic appliance.

Phase 3
Conditions
Health Condition 1: K089- Disorder of teeth and supporting structures, unspecified
Registration Number
CTRI/2023/09/057246
Lead Sponsor
Alwin Johnson
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

1. Patients who require extraction of all first premolars in their treatment protocol.

2. patients with mandibular anterior crowding with Littles irregularity index more than 10mm.

3. patients without any clinical or radiographic signs of periodontal disease.

4. patients with sound general health without any systemic disease.

5. patients who will request for reduced treatment period.

6. patients who will consent to participate in the study.

Exclusion Criteria

1. Patients on antibiotics, anti-inflammatory or steroids.

2. Presence of primary teeth or missing permanent teeth other than third molars in the mandibular arch.

3. Patients requiring orthognathic surgery.

4. Patients with any congenital cranio-facial anomaly or affected by craniofacial syndromes.

5. Patients with pre-existing psychiatric or undergoing psychiatric therapy.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Time required for alignment of crowded lower anterior teethTimepoint: T0- Starting of the treatment. <br/ ><br>T1- End of 1st month. <br/ ><br>T2- End of 2nd month. <br/ ><br>T3- End of 3rd month. <br/ ><br>T4- End of 6th month.
Secondary Outcome Measures
NameTimeMethod
Pain perceptionTimepoint: 24 Hours, 1 week, End of 1 month;Root resorption of lower anterior teeth undergoing micro-osteo perforation with orthodontic mini-implants.Timepoint: T0- Starting of treatment. <br/ ><br>T1- At the end of sixth month.
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