Gastroesophageal Reflux Disease and Probiotics
Not Applicable
- Conditions
- Gastroesophageal Reflux DiseaseGERD
- Registration Number
- LBCTR2023105464
- Lead Sponsor
- ebanese American University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 400
Inclusion Criteria
•Patients with mild to moderate GERD symptoms (diagnosed on basis of clinical presentation)
•Patients with GERD regardless of prior treatment for GERD but not currently on PPIs over at least 4 weeks
Exclusion Criteria
•Patients less than 18 years or above the age of 50
•Prior bariatric surgery
•Epigastric mass
•Prior endoscopy showing severe erosive esophagitis LA-C or LA-D
•Alarm symptoms: weight loss, anemia, dysphagia or odynophagia, family history of malignancy, melena, hematemesis, nausea and vomiting
•Pregnant women
•Malignancy, IBD, immunosuppressive therapy
•Advanced cardiac disease
•Chronic uninterrupted use of PPI
•ESRD
•Use of probiotics within the last 6 months
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method ame: Gastroesophageal Reflux Disease Symptoms;Timepoints: 8 weeks;Measure: The Gastroesophageal Reflux Disease-Health Related Quality of Life instrument
- Secondary Outcome Measures
Name Time Method