Comparison of Clinical Outcomes between Twice- and Thrice- Weekly Hemodialysis in Thai Elderly Patients at Bhumirajanakarindra Kidney Institute Hospital
Not Applicable
- Conditions
- End stage renal disease Receiving twice or thrice weekly hemodialysis
- Registration Number
- TCTR20171231003
- Lead Sponsor
- Bhumirajanakarindra Kidney Institute Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending (Not yet recruiting)
- Sex
- All
- Target Recruitment
- 200
Inclusion Criteria
1. Age 65 years or older
2. Have been diagnosed with end stage renal disease
3. Receving twice or thrice weekly hemodialysis regularly at Bhumirajanakarindra Kidney Institute Hospital at least 3 months before enrollment
3. Signed written informed consent approved by the Ethical Review Committee for Research in Human Subjects, Ministry of Public Health
Exclusion Criteria
History of previous peritoneal dialysis or kidney transplantation
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method composite end points of all-cause mortality, cardiovascular events, hospitalization from any cause 36 months rate/patient-year
- Secondary Outcome Measures
Name Time Method All-cause mortality 36 months rate/patient-year,Death from cardiovascular cause 36 months rate/patient-year,Cardiovascular events 36 months rate/patient-year,Hospitalization from any infection 36 months rate/patient-year,Hospitalization from cardiovascular events 36 months rate/patient-year,Health related quality of life every 6 months KDQOL-36 score (Thai version),Caregiver burden every 6 months Scale by Zarit Burden Interview (Thai version),Residual renal function every 6 months Kr (ml/min/1.73m2), urine volume (ml),Adequacy of hemodialysis every 6 months stdKt/V per week,Nutritional status every 6 months nPCR, serum albumin (g/dL),Markers of metabolic bone disease every 6 months Serum calcium (mg/dL), phosphate (mg/dL), parathyroid hormone (pg/mL),Anemia every 6 months Hb (g/dL), ESA dose (units/week),Vascular access complication 36 months rate/patient-year,Vascular access complication 36 months rate/patient-year