Effect of diphenhydramine and granisetron on the prevention of postoperative nausea and vomiting and pain after laparoscopic cholecystectomy
Not Applicable
Recruiting
- Conditions
- Condition 1: Postoperative nausea and vomiting. Condition 2: Postoperative pain.Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedureOther complications of anesthesiaT88.59
- Registration Number
- IRCT20150125020795N7
- Lead Sponsor
- Tabriz University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 120
Inclusion Criteria
All of Patients at age of 18 to 59 who Being a Candidate for Elective Surgery and Based on ASA Classification are 1 or 2 ASA Class.
Exclusion Criteria
Patients under Prescription of anti-nausea Drugs in the last 24 hours.
Patients with Cardiovascular, Hepatic , Kidney ,blood pressure and hyperadiposis Disease
pregnant women and during menstruation
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Severity of postoperative nausea and vomiting. Timepoint: Recovery and at 3, 6, and 24 h postoperatively. Method of measurement: scoring by (0=non, 1=nausea, 2=vomiting, 3=vomiting >2 times).
- Secondary Outcome Measures
Name Time Method Severity of pain after injection of diphenhydramine and granisetron. Timepoint: Amount of pain evaluate on 5, 10, 15 and 20 seconds after injection of diphenhydramine and granisetron. Method of measurement: Four Numerical Verbal Rating Scale.