Clinical trial the effect of granisetron and dexamethasone on intravenous propofol pain in patient whit dilatation and curettage surgery
Phase 2
- Conditions
- Pain of propofol injection.Generalized pain NOS
- Registration Number
- IRCT2017040427677N6
- Lead Sponsor
- Vice Chancellor for research of Urmia University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 141
Inclusion Criteria
physical status class I and II from the perspective of America society of Anesthesiologists; dilatation and curettage surgery; 20 to 50 years old
Exclusion criteria: Patients with a history of Allergies to propofol or 5-hydroxytryptamine receptor antagonists or dexamethasone; Patients who received any medication for analgesia or sedation in the past 24 hours; Severe mental disorders; Neuromuscular disease; ischemic heart disease; Uncontrolled hypertension; Renal and hepatic disease; Convulsion disease; Body mass index over 30; Chronic use of any drugs; Gastrointestinal disorders; History of osteoporosis; History of diabetes
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pain of propofol injection. Timepoint: Induction of Anesthesia. Method of measurement: visual analog scale.
- Secondary Outcome Measures
Name Time Method Mean pulse Rate. Timepoint: Before injection, 1, 3, 5, 10 minutes after injection. Method of measurement: Electrocardiogram.;Mean Arterial Blood Pressure. Timepoint: Before injection, 1, 3, 5, 10 minutes after injection. Method of measurement: None Invasive Blood Pressure.;Os saturation. Timepoint: Before injection, 1, 3, 5, 10 minutes after injection. Method of measurement: Pulse Oximetry.