The study is to compare the two groups of drugs for prevention of vomiting after surgery
Phase 3
- Conditions
- Health Condition 1: H661- Chronic tubotympanic suppurative otitis mediaHealth Condition 2: H673- Otitis media in diseases classified elsewhere, bilateralHealth Condition 3: H679- Otitis media in diseases classified elsewhere, unspecified ear
- Registration Number
- CTRI/2022/12/047871
- Lead Sponsor
- VIMSAR
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
ASA I,II with 20 to 65yrs both male and female are selected who are posted for Middle ear surgeries
Exclusion Criteria
Pregnancy, patient with BMI >35, smokers, history of PONV/motion sickness, abnormal liver and kidney function test, patient with Diabetes and peptic ulcer are excluded from the study
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The incidence of PONV and rescue antiemetic requirements in granisetron and dexamethasone group is less than ondansetron and dexamethasone groupTimepoint: Time points at which variables are measured are 0hr, 2hr, 6hr, 12hr & 24hr postoperatively
- Secondary Outcome Measures
Name Time Method Rescue antiemetic requirements <br/ ><br>Rescue analgesic requirementsTimepoint: Within 48 hour of post-operative period